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Jacob Jones

Jacob Jones

Associate Professor


Associate Professor
Office Phone(909) 537-5590
Office LocationSB-531


Ph.D Clinical Psychology, University of Florida, 2016; M.S. Clinical Psychology, University of Florida, 2012; B.A. Psychology, California State University Channel Islands, 2009

Research and Teaching Interests

My research interests generally include investigating the underlying neural mechanisms of neuropsychiatric symptoms in neurodegenerative disorders, such as Parkinson’s disease. Studies utilize structural neuroimaging methods and/or longitudinal statistical modeling to examine predictors of cognitive impairment, apathy and depression. One line of research is testing the hypothesis that disruptions in the microbiome (gut-brain health) contribute to cognitive impairment and white matter changes in Parkinson’s disease. A second line of research focuses on relating neuropsychiatric symptoms to meaningful outcomes such as diagnostic markers of cognitive impairment and quality of life.

Selected Publications (for complete list click here):

Jones, J. D., *Uribe-Kirby, R., *Rivas, R., *Cuellar-Rocha, P., *Valenzuela, Y., *Luna, K., Dashtipour, K., Santos, M. (2023). Mental Health Disparities and the Role of Perceived Discrimination among Latinx Individuals Living with Parkinson’s Disease. Parkinsonism & Related Disorders. 

*Hemphil, L., *Valenzuela, Y., *Luna, K., Szymkowicz, S.M., Jones, J. D. (2023). Synergistic Effects of Depressive Symptoms and Aging on Cognitive Decline in Early Parkinson’s Disease. Clinical Parkinsonism & Related Disorders. 

Jones, J. D., * Rivas, R., *Luna, K., *Ryczek, C., Thomas, K. R. (2023). Subjective Cognitive Complaints Are Important in PD-MCI Criteria: Associations with CSF Markers and Cognitive Decline. Parkinsonism & Related Disorders. doi: 10.1016/j.parkreldis.2022.11.013.

Jones, J. D., *Baxter, F., *Timblin, H., *Rivas, R., Hill, C. R., (2022). Physical Inactivity is Associated with Parkinson’s Disease Mild Cognitive Impairment and Dementia. Mental Health and Physical Activity. 

Jones, J. D., *Timblin, H., *Baxter, F. (2022). Cumulative Effect of Head Injuries on Non-Motor Outcomes in Parkinson’s Disease. Journal Neuropsychiatry & Clinical Neurosciences. 

*Timblin, H., *Rahmani, E., *Ryczek, C., Hill, C. R., Jones, J. D. (2022). Physical Inactivity Links Depressive Symptoms and Cognitive Functioning among Individuals with Parkinson’s Disease. Neuropsychology.

Jones, J. D., *Valenzuela, Y., *Uribe, C., *Bunch, J., Kuhn, T. P. (2022). Intra-Individual Variability in Neuropsychological Performance Predicts Longitudinal Cortical Volume Loss in Early Parkinson’s Disease. Neuropsychology.

Jones, J. D., *Dominguez, B., *Bunch, J., *Uribe, C., *Valenzuela, Y., & Jacobs, J. P. (2021). A bidirectional relationship between anxiety, depression and gastrointestinal symptoms in Parkinson’s disease. Clinical Parkinsonism & Related Disorders. 5, 100104.

Jones, J. D., *Timblin, H., *Rahmani, E., *Garrett, S., *Bunch, J., *Beaver, H., Hill, C. R. (2021). Physical Activity as a Mediator of Anxiety and Cognitive Functioning in Parkinson’s Disease. Mental Health and Physical Activity. 20, 1-6

Jones, J. D., *Uribe, C., *Bunch, J., Thomas, K. R. (2021). Beyond PD-MCI: Objectively Defined Subtle Cognitive Decline Predicts Future Cognitive and Functional Changes. Journal of Neurology. 268(1), 337-345.

Jones, J. D., *Rahmani, E., *Garcia, E., Jacobs, J. P. (2020). Gastrointestinal Symptoms are Predictive of Trajectories of Cognitive Functioning in De Novo Parkinson’s Disease. Parkinsonism & Related Disorders. 72, 7-12.

Jones, J. D., Kurniadi, N. E., Kuhn, T. P., Szymkowicz, S. M., *Bunch, J., *Rahmani, E. (2019). Depressive Symptoms Precede Cognitive Impairment in De Novo Parkinson’s Disease Patients: Analysis of the PPMI Cohort. Neuropsychology. 33(8), 1111-1120.

Jones, J. D., *Burroughs, M., *Apodaca, M., *Bunch, J. (2019). Greater Intra-Individual Variability in Neuropsychological Performance Predicts Cognitive Impairment in De Novo Parkinson’s Disease. Neuropsychology. 34(1), 24-30.

*denotes student co-authors



NIH/NINDS 1SC3NS124906-01; PI: Jones; 5/01/2021 – 4/30/2025 “Microbiome Composition and Function Contribute to Cognitive Impairment and Neuroinflammation in Parkinson’s Disease.” Disruption of the gut-microbiome may be a novel mechanism underlying cognitive impairment. The goal of this study is to determine the association between microbiome disruption and markers of neuroinflammation/cognitive impairment. $440,00

NIH/NIA R01 AG064493-03; PI: Nelson; 4/1/2022 – 5/31/2024 “URBAn Native Elders (URBANE): Risk and Protective Factors for Alzheimer's and Related Dementias.” Alzheimer’s disease and related disorders (ADRD) is a growing public health concern for American Indian and Alaska Native (AI/ANs) people, but AI/ANs are profoundly underrepresented in ADRD research. This study will quantify the extent of probable ADRD and VBI as defined by brain MRI, and determine their associations with cognitive functioning in a diverse sample of urban AI/AN elders. Subaward amount: $735,329. Role: Co-Investigator/Sub-Award PI

NIH/NIGM T34 GM136467-03; PI: Crawford 4/1/2020 – 3/31/2025. “U-RISE at California State University San Bernardino.” $2,526,950. Role: Co-Investigator/Associate Director.

NIH/NIA R16 AG086053; PI: Vogelsang; 8/15/2023-4/30/2027 “Older Adult Social Participation, Gender, and Cognitive Decline.” $748,000. Role: Co-Investigator

American Psychological Association SCN Early Career Pilot Award; Role: PI; 7/1/2018-6/30/2019 “The Gut-Brain Axis in Parkinson’s Disease: Influences of Microbiota on Cognition and White Matter Integrity.” $14,970.